March 09, 2010

Vitamin D to combat Crohn's

Two new studies have pointed to Vitamin D having a role in fighting Crohn's. Scientists believe that the boost to the immune system provided by Vitamin D could benefit Crohn's sufferers, and perhaps ensuring adequate Vitamin D levels could prevent Crohn's from occurring.

As noted in Science Daily:

Dr. White and his team found that Vitamin D acts directly on the beta defensin 2 gene, which encodes an antimicrobial peptide, and the NOD2 gene that alerts cells to the presence of invading microbes. Both Beta-defensin and NOD2 have been linked to Crohn's disease. If NOD2 is deficient or defective, it cannot combat invaders in the intestinal tract.


The Telegraph states:
“Scientists have known for a long time that vitamin D is important for calcium absorption and the vitamin has also been implicated in diseases such as cancer and multiple sclerosis, but what we didn’t realise is how crucial vitamin D is for actually activating the immune system – which we know now, ” said the researchers.


It's interesting that these different mechanisms for Vitamin D to enhance the immune systems have been reported on almost simultaneously. Although their link to Crohn's is speculative, it opens further avenues for research. Who wouldn't hope for a cod liver oil tablet cure?